Depends on what it's for, I'd say. For example, I wouldn't necessarily want one as an engagement or wedding ring. Yes, they're absolutely identical to the real thing (and usually better, in fact, because they're flawless and grown in an ideal environment). I think the best way I've heard lab-created vs natural described is the difference between a rose grown in a garden vs. a rose grown in the yard. A rose is still a rose!
If I''m not mistaken, they also come in several qualities. I''ve heard that Chatham makes very nice looking lab created sapphires. Personally, I prefer something that nature made, through the upheaval of heat, pressure and time to create something incredibly beautiful.
A friend of mine got a gorgeous lab grown sapphire e-ring with a Chatham sapphire. One of the nice things about them is that you can pick exactly the tone, saturation, color, etc, that you want. That said, its your ring and only you will know if its "birth" will bother you.
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