I have a pendant that is in that style with a bezel. The culet does poke me and I notice it, but never have been scratched. I have a similar DBTY bracelet but the bezels are thicker and the stones are pretty small so the culets don't extend past the bezels so no poking.
It is impossible for them to poke you unless there is pressure applied to them. Technically it could happen with your wrist if you lay your wrist on a surface where the bracelet was pressed against your skin. I have not had that problem, however.