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Coronavirus updates March 2021...please add yours.

missy

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missy

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“ A curve ball for South Africa’s vaccinations

A fierce debate is raging in South Africa over how best to approach its coronavirus vaccination campaign following the emergence of a virulent new variant that was first identified in the country late last year and now accounts for almost all its new infections.

The government suspended plans to begin dispensing vaccines developed by AstraZeneca and the University of Oxford to health-care workers at the eleventh hour last month, after a clinical trial showed they offered little protection against mild to moderate infections with the B.1.351 strain. The study didn’t determine whether the shots protected against severe Covid-19 cases and deaths because most of the 2,000 participants were young healthy adults.

The last thing South Africa needs is to inoculate a large swathe of the population and then have to do it all over again, according to Salim Abdool Karim, an epidemiologist who co-chairs the nation’s ministerial advisory committee on Covid-19. The government has now switched to using a single-shot vaccine developed by Johnson & Johnson that has proved effective against the new variant, and is negotiating to buy other shots from Pfizer.


Health care workers receive vaccines.
Photographer: Gallo Images/Gallo Images Editorial
Shabir Madi, a vaccinology professor at the University of Witwatersrand and the lead researcher of the South African trial of the AstraZeneca vaccines, says there remains a strong likelihood they will prevent severe disease since they rely on the same viral vector technology as the J&J shot, and it’s a mistake not to use them. He favors inoculating high-risk individuals because the country won’t be able access sufficient alternatives for months, leaving them with no protection at all.

Madi’s assertions remain unproven, and plans to conduct another study into AstraZeneca vaccines’ efficacy have been shelved because the government says it has more pressing priorities. The World Health Organization last month advocated the continued use of the AstraZeneca shot, even in places where virus mutations are circulating.

A number of nations, including Ireland and the Netherlands subsequently
suspended use of AstraZeneca's vaccines as a precautionary measure amid concerns that they raised the risk of blood clots. The company says more than 17 million doses had been administered in Europe and the U.K., with no evidence that they had adverse side effects.

South Affrica’s government isn’t taking any chances for now—it’s in talks to sell the 1 million AstraZenca vaccines it acquired from the Serum Institute of India to an African Union facility so they can be used by other nations on the continent.

The debate as to whether the country should have hung onto its allocation will likely be settled in coming months. The South African strain is now present in almost 50 other countries, some of which are already using the shot or intend doing so.

South Africa has Africa’s worst coronavirus outbreak, with more than 1.5 million infections detected so far. New cases have plummeted since reaching a peak in January, but fears are mounting that a third wave will hit as the country heads into winter.—Mike Cohen”
 

Austina

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This ‘issue’ has been mentioned in another post, so I thought I’d post it here too. There are a lot of politics involved with the roll out of vaccines in other countries, and it suits their agenda to basically rubbish the vaccine.
 

voce

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@voce I think you asked a question about this. HTH.



missy, this is not exactly my concern. My question was not whether the *adenovirus* DNA would affect human DNA, as I understood the part about the virus being only a vector with its own portion of DNA governing reproduction knocked out. However, the engineered piece of DNA encoding for the spike protein--THAT was what I really was concerned about, whether the engineered DNA fragment would integrate with human DNA during mitosis.

You can't exactly say it never happens, because a significant portion of human DNA contains fragments from prehistoric viruses and bacteria, only that it is statistically insignificant. I am perfectly capable of reading medical research papers and staying my own conclusions, and I did satisfy my own curiosity that the frequency of integration with human DNA is super low, between 1 in 1,000 and 1 in 100,000.
 

missy

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@voce glad you found your answer.
FYI for others who might be interested here’s more info.

 

MaisOuiMadame

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Hi @Austina , could you please elaborate on the political agenda that makes Denmark, Norway, Thailand , Germany, Italy, France, the Netherlands (plus Estonia, Latvia, Luxembourg and Lithuania for a certain batch) poop that vaccine? I'm the last person to say that things have been going perfect over here, but the British press seem to have reported certain facts a bit biased since Brexit (the story of Parisians fleeing the city in November comes to mind).

There have been new findings of very very rare cervical blood clots after AZ vaccines which have experts alarmed. That's the reason for the suspension at least in the countries where I follow the press closely.

Denmark , the first country to suspend for example shouldn't have a specific agenda..
 

missy

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Karl_K

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apt for sat for the first shot it would not let me request which one but leaning towards rejecting j&j if that is all they can offer.
The science just does not support it for someone very high risk compared to the other 2 vaccines.
 

Austina

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This is just one of many such articles I’ve read @kipari

 
Last edited:

missy

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Europe’s vaccine mess​

It is the latest sign of the power of the Covid-19 vaccines: The number of new cases is declining, often sharply, in countries that have vaccinated a large share of residents.​
That’s the situation in Israel, the United Arab Emirates and Britain. Cases are also declining in the U.S., which is not as far along as those three countries but is well ahead of most.​
And on the other end of the spectrum is the European continent.​
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By The New York Times | Sources: Health agencies and hospitals​
Across most of the European Union, vaccine rollout has been slow, and new cases are surging. Europe — the first place where the coronavirus caused widespread death — is facing the prospect of being one of the last places to emerge from its grip. My colleague Jason Horowitz writes from Rome: “Governments are putting exhausted populations under lockdown. Street protests are turning violent. A year after the virus began spreading in Europe, things feel unnervingly the same.”​
As Eyck Freymann and Elettra Ardissino write in Foreign Policy: “Spring in the European Union is going to be dismal.” Bild, a German newspaper, recently ran the headline “Liebe Briten, We Beneiden You!” — a mixture of German and English that means “Dear Brits, We Envy You!” Wolfgang Münchau of Eurointelligence has said that Europe’s vaccination program rivals the continent’s budget austerity of recent years as “the E.U.’s worst policy error during my lifetime.”​
Why has Europe done so poorly? There are three main reasons.​

1. Too much bureaucracy​

While the U.S. and other countries rushed to sign agreements with vaccine makers, the E.U. first tried to make sure all 27 of its member countries agreed on how to approach the negotiations. Europe chose “to prioritize process over speed and to put solidarity between E.U. countries ahead of giving individual governments more room to maneuver,” Jillian Deutsch and Sarah Wheatonwrite for Politico Europe.​
The result was slower regulatory approval of the vaccines and delayed agreements to buy doses, forcing Europe to wait in line behind countries that moved faster.​

2. Penny-wise and pound-foolish​

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A park in Milan this week.Alessandro Grassani for The New York Times​
Europe put a big emphasis on negotiating a low price for vaccine doses. Israeli officials, by contrast, were willing to pay a premium to receive doses quickly. Israel has paid around $25 per Pfizer dose, and the U.S. pays about $20 per dose. The E.U. pays from $15 to $19.​
The discounted price became another reason that Europe had to wait in line behind other countries. Even in purely economic terms, the trade-off will probably be a bad one: Each $1 saved per vaccine dose might ultimately add up to $1 billion — a rounding error in a trading bloc with a nearly $20 trillion annual economic output. A single additional lockdown, like the one Italy announced this week, could wipe out any savings.​
“The price difference is macroeconomically irrelevant,” Münchau writes. The E.U. “tried to lock in a perceived short-term price advantage at the expense of everything else.”​

3. Vaccine skepticism​

“Europe is the world’s epicenter of vaccine skepticism,” Deutsch and Wheaton of Politico Europe write. That skepticism predated Covid, and now its consequences are becoming clear.​
In a survey published in the journal Nature Medicine, residents of 19 countries were asked if they would take a Covid vaccine that had been “proven safe and effective.” In China, 89 percent of people said yes. In the U.S., 75 percent did. The shares were lower across most of Europe: 68 percent in Germany, 65 percent in Sweden, 59 percent in France and 56 percent in Poland.​
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A train station in Athens, Greece.Byron Smith for The New York Times​
The skepticism helps explain Europe’s latest vaccination problem. About a dozen countries, including France and Germany, have suspended the use of one of the continent’s primary vaccines, from AstraZeneca, citing concerns about blood clots.​
But the evidence that the vaccine causes clots is thin. Europe’s main drug regulator still says the benefits outweigh the risks. And Ann Taylor, AstraZeneca’s chief medical officer, has pointed out that the rate of clotting among vaccinated Europeans is lower than “would be expected among the general population.”​
Dr. Muge Cevik, a virus expert at the University of St. Andrews, told me yesterday that it was always important to scrutinize vaccines. But, she added, “I would say the benefits of the A.Z. vaccine in preventing Covid, hospitalization and death outweigh the risks of side effects, especially in the middle of the pandemic.”​
The bottom line: Over the summer, the U.S. was struggling more than any other country to contain Covid. Today, Europe appears to be in much worse shape.​
 

missy

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"New Covid-19 vaccines—including drugs that don’t require needles and can be stored at room temperature—may be ready for use later this year, the World Health Organization’s top scientist said. In Europe, such advances can’t come soon enough: Germany suspended use of AstraZeneca’s shot amid a growing scare over blood clots, creating yet another delay for the European Union’s inoculation campaign. In other countries, lockdowns are falling into place again as infection rates trend upward. Even in the U.S., where vaccination is speeding up and states are throwing open their doors (despite the looming threat of variants), at least 572 Americans died from the virus on Sunday alone, with a seven-day average of 1,400 fatalities every day. There were 38,000 new U.S. infections reported on Sunday, with a seven-day average of 54,000 per day. Worldwide, the WHO warned that there was an 11% transmission spike in just the past week. Here’s the latest on the pandemic. —David E. Rovella
"

 

missy

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Hard-hit countries face big vaccine bills​

Colombia has already paid a steep price in the pandemic with more than 61,000 deaths from Covid-19. Now the South American nation faces another cost: about $850 million to immunize its population.
With an annual health budget of just $10 billion for about 50 million residents, Colombia is one of many countries struggling to afford immunizations. Health-care advocates have said that drugmakers hold the upper hand in negotiations with governments that have limited cash and aren’t eligible for free doses.
Colombia has reported 2.3 million Covid cases, or about two out of every 100 worldwide. Tougher restrictions in major cities, fueled by rising infections at the start of the year, hampered recovery from its deepest economic contraction in history, and the government is planning tax increases and spending cuts.
Countries like Colombia “are against the wall,” said Carolina Gomez, co-founder of an advocacy group at Universidad Nacional de Colombia that works to ensure access to medicines and health technology. “They have no choice but to submit to what the drugmakers say.”
Covax, a program backed by the World Health Organization and other groups that aims to deploy shots equitably to every corner of the globe, is helping many poor countries access immunizations by providing doses funded by donors. But it can’t cover the costs for countries like Colombia or supply enough to protect most of a country’s population.
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A health worker carries a container of Pfizer-BioNTech vaccines at a clinic in Bogota, Colombia.
Photographer: Nathalia Angarita/Bloomberg
So Colombia has done direct deals for doses needed to supplement its purchases via Covax. The country agreed to buy 10 million doses from partners Pfizer and BioNTech at $12 each, regulatory filings show.
It’s paying about $295 million for 10 million Moderna doses, according to Finance Ministry documents pointed out by researchers from Universidad Javeriana in Bogota. That’s equivalent to almost $30 a dose, although it may include logistics expenses. The cost of 20 million doses through Covax comes to roughly $225 million. The figures take into account some transport costs. Officials declined to provide more details.
High- and middle-income countries will pay more than low-income nations for Pfizer’s shot, but at a significant discount from “normal benchmarks” during the pandemic, the company said. Pfizer said it won’t profit off supplies to poorer countries. Moderna didn’t respond to requests for comment.
South Africa, which budgeted as much as 19.3 billion rand ($1.3 billion) to vaccinate two-thirds of its population, confronted a similar dilemma. After a small study indicated AstraZeneca’s shot offered minimal protection against mild to moderate illness caused by a new variant, it had to change course.
The government agreed to buy doses of both Johnson & Johnson’s single-shot vaccine as well as the Pfizer-BioNTech product at $10 each, according to its health department. It committed $5.25 a dose for AstraZeneca’s vaccine made by the Serum Institute of India. Moderna offered vaccines at between $30 and $42 per dose, but South Africa hasn’t announced any orders.
Such payments are spread out across the globe. In another example, Malaysia has estimated its vaccine costs at about 3 billion ringgit ($730 million). The healthy ministry’s 2021 budget is less than $8 billion for its population of about 33 million.
The expenses for these countries may not seem like a huge price to pay compared with the size of their economies and the overall cost of the pandemic, but they’re adding to the pain for those governments.
“Up until now the landscape has been defined by availability,” said Safura Abdool Karim, a public health lawyer and researcher at the Wits School of Public Health in Johannesburg. “It will increasingly be defined by affordability.”—James Paton and Andrea Jaramillo
 

missy

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"
The biggest vaccination campaign in history is underway. About 392 million doses have been administered across 128 countries, according to data collected by Bloomberg. The latest rate was roughly 9.50 milliondoses a day.
In the U.S., more Americans have received at least one dose than have tested positive for the virus since the pandemic began. So far, 111 milliondoses have been given. In the last week, an average of 2.44 million doses per day were administered.


When will life return to normal?​

While the best vaccines are thought to be 95% effective, it may still be possible to spread the disease after getting inoculated. Anthony Fauci, the top infectious-disease official in the U.S., has said that vaccinating 70% to 85% of the U.S. population would enable a return to normalcy.
On a global scale, that’s a daunting level of vaccination. At the current pace of 9.50 million a day, it would take years to achieve a significant level of global immunity. The rate, however, is steadily increasing, and new vaccines by additional manufacturers are coming to market.

The Path to Immunity Around the World​



Note: Immunity calculations take into account the two doses required for most vaccines. The “daily rate estimate” is a seven-day rolling average; interpolation is used for countries with infrequent updates. Data are from Bloomberg’s Covid-19 Vaccine Tracker.
Did we miss a country? Drop us a link
Since the start of the global vaccination campaign, countries have experienced unequal access to vaccines and varying degrees of efficiency in getting shots into people’s arms. Before March, few African nations had received a single shipment of shots. In the U.S., 33.4 doses have been administered for every 100 people.
Delivering billions of vaccines to stop the spread of Covid-19 worldwide will be one of the greatest logistical challenges ever undertaken.

Race to End the Pandemic​

Israel leads all countries with 104.5 doses per 100 people


Note: Two doses are needed for full protection with most vaccines currently in use. Data from Bloomberg’s Covid-19 Vaccine Tracker

Global Vaccination Campaign​



Note: The average daily rate is a 7-day average; for countries that don’t report daily, the last-known average rate is used.

U.S. Vaccinations: State by State​

The U.S. leads the world in total vaccines administered, and more supply is on the way. Drugmakers have promised to deliver enough shots to fully vaccinate 130 million Americans by the end of March and 300 million people by the end of May. That’s more than enough for every adult, and clinical studies in children are underway.
After focusing first on hospitals and other institutional health-care settings, states have opened access to increasingly larger groups of people: essential workers, teachers, people over 65 and younger adults with pre-existing health conditions. As supply has increased, some states are making mass vaccination centers out of sport stadiums, theme parks, convention halls and race tracks.

Vaccines Across America​

Across the U.S., 33.4 doses have been administered for every 100 people, and 77% of the shots delivered to states have been administered.



Note: Data added after Feb. 20 is from the CDC and includes doses administered by federal entities in state totals. Figures for partial or complete vaccinations refer only to a state’s residents, regardless of where their shots were administered. Historic data gathered from local and federal government websites, official statements and Bloomberg interviews. It can take several days for counts to be reported through the CDC database.
Distribution in the U.S. is directed by the federal government. Pfizer and BioNTech’s vaccine, as well as Moderna’s shot both require two doses taken several weeks apart. J&J’s inoculation requires just a single dose.
The introduction of J&J’s one-shot option in March is speeding up vaccinations and making it easier to vaccinate hard-to-reach populations. So far, 72.1 million Americans have received at least one dose of a vaccine, or roughly a quarter of the adult population. At least 39 million people have completed a vaccination regimen.

Tips and Feedback: Help us improve the Covid-19 Vaccine Tracker

The Path to Immunity in the U.S.​



Note: Vaccinating roughly 70% to 85% of a country’s population would enable a return to normalcy, according to top U.S. infectious disease doctor Anthony Fauci. Immunity calculations take into account the two doses required for the Pfizer and Moderna vaccines. Data are from Bloomberg’s Covid-19 Vaccine Tracker.
It takes about two weeks after a final vaccine dose for immunity to fully develop. After that, a person can safely meet indoors with other vaccinated people without wearing masks, according to CDC guidance issued in March. Grandparents can spend time with their grandchildren again.
Even for people fully vaccinated, some restrictions remain in place while the virus still circulates across the country. The CDC advises against travel and recommends wearing masks and social distancing while in public.

How State Vaccinations Stack Up​

Alaska leads all states with 46.4 doses administered per 100 people


Note: Two doses are needed for full protection with the Pfizer and Moderna vaccines, while the J&J shot requires a single dose. Data from Bloomberg’s Covid-19 Vaccine Tracker

U.S. Vaccination Campaign​



Note: The category entry for Federal Entities isn’t counted in the country total because those vaccinations are already included in relevant state totals. The “Unassigned” entry refers to vaccinations from CDC’s U.S. totals that the agency didn’t assign to a specific state or territory. “Doses administered” figures include all vaccinations within a state, regardless of a person’s residency, while population coverage data only accounts for residency. “Shots used” shows the proportion of administered vaccines compared with the total doses received by a state.

Vaccine Timeline​

Bloomberg is tracking the development of nine of the globe’s most promising vaccines. A total of seven vaccines are now available for public use, in limited quantities, in at least 128 countries.
Nations have poured billions of dollars into developing new vaccine technologies, testing them in thousands of volunteers, scaling up manufacturing, and then bringing them to market in record time.

None of these shots, on its own, is enough to inoculate a global population of some 7.8 billion people. But together they represent humanity’s best chance of ending a scourge that has claimed more than 2.6 million lives and triggered global economic calamity.

"
 

missy

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MrsBlue

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apt for sat for the first shot it would not let me request which one but leaning towards rejecting j&j if that is all they can offer.
The science just does not support it for someone very high risk compared to the other 2 vaccines.

The portal I used posts which vaccine is available at each location. I've never seen a location offer more than one type of vaccine at a time so you may be able to call ahead and ask what they have.

Good luck!
 

Austina

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British Prime Minister, Boris Johnson is having his first jab tomorrow, and will be getting the Astra Zeneca/Oxford vaccine.
 

YadaYadaYada

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This is really only helpful to Connecticut residents but if you schedule to get a shot through Hartford Healthcare, you can choose which brand you want:

 

Karl_K

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The portal I used posts which vaccine is available at each location. I've never seen a location offer more than one type of vaccine at a time so you may be able to call ahead and ask what they have.

Good luck!
In IL it is being ran at the county level and their is no one to call in my county.
The site my appointment is at is ran by the national guard but you have to get an appointment from the county to get a shot.
They have been using all 3 based on what they have available so its a crap shoot.
 

MamaBee

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apt for sat for the first shot it would not let me request which one but leaning towards rejecting j&j if that is all they can offer.
The science just does not support it for someone very high risk compared to the other 2 vaccines.
@Karl_K I agree with you. The experts say to take whatever vaccine is offered to you...My son and daughter-in-law agree with them and will take any vaccine that they are offered. I would have waited for Moderna or Pfizer...because I’m older. I just completed my shots last week. I received the Moderna vaccine. One week to go and I’m fully vaccinated. I read that the vaccines may only protect for three to four months. They don’t have the data yet. That would be so disappointing..
 

Austina

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They‘re working on a booster here @MamaBee, talking about giving it in August/September time.
 

MamaBee

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They‘re working on a booster here @MamaBee, talking about giving it in August/September time.

I hope we also get a booster...What vaccine did you get @Austina? I know you told me once before but my brain is scrambled with all that’s going on with my mom...
 

Calliecake

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In IL it is being ran at the county level and their is no one to call in my county.
The site my appointment is at is ran by the national guard but you have to get an appointment from the county to get a shot.
They have been using all 3 based on what they have available so its a crap shoot.

@Karl_K , It was announced today that Illinois Covid vaccines will be eligible to all adults outside of Chicago on April 12. I’m hoping you get your vaccine soon.
 

Austina

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We’ve both had our first dose of Pfizer @MamaBee, our Dr’s are starting the recall for the second shot today, so shouldn’t be too much longer for us.
 

TooPatient

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My friend from growing up through school together was supposed to bake my birthday cake and couldn't due to testing positive. Her two kids also tested positive, but they were asymptomatic. She had minor symptoms but still has no sense of smell or taste. This is very difficult for her because she loves food and because she runs her own cake baking business and was working at expanding to some catering using recipes she was creating. Very hard to do if you can't smell or taste!

Another person I went to school with had her family all test positive. No major symptoms. Just a cold really. Until last week... Her 15 year old son got very sick about 10 weeks after having it. Multiple emergency room visits as he got sicker ending with nearly a week in critical care. She is doing her best to share their story as she had no idea that could happen in kids.
 

MrsBlue

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In IL it is being ran at the county level and their is no one to call in my county.
The site my appointment is at is ran by the national guard but you have to get an appointment from the county to get a shot.
They have been using all 3 based on what they have available so its a crap shoot.

Eek that sounds like a logistical nightmare, especially for getting the 2nd shot. I'm glad the national guard is assisting!

Best of luck with your appointment. Take care of yourself and get plenty of rest.
 

MamaBee

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We’ve both had our first dose of Pfizer @MamaBee, our Dr’s are starting the recall for the second shot today, so shouldn’t be too much longer for us.

Thank you @Austina I thought you both had Pfizer but I wasn’t sure. That’s great that they are thinking of booster shots. I’ve been feeling low since I read yesterday that they don’t know how long immunity lasts after receiving the vaccine. I had the Moderna vaccine...My daughter-in-law told me yesterday that even after they get their shots..our “window” will be different..and the children won’t be vaccinated. We would have to visit them outside with masks on. She said I may be able to briefly hold the baby with a mask outside. After all the trouble trying to find a vaccine for us...we won’t be able to hold and baby and go inside their house...I hope data comes out that says the vaccines last longer than three months...:confused:
 

missy

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I’ve been feeling low since I read yesterday that they don’t know how long immunity lasts after receiving the vaccine.

Aww Joanne try not to worry. It probably will last longer than a few months. We don’t have definitive evidence only because it has only been studied since the summer of 2020. And they are working on a booster that will likely extend the duration of efficacy. We hope.


“ Since the vaccines have been tested only since the summer of 2020, we do not have information about the durability of protection. Data from the phase 1 trial of the Moderna vaccine suggested that neutralizing antibodies persisted for nearly 4 months. opens in new tab, with titers declining slightly over time. Given the absence of information on how long the vaccines will be protective, there is currently no specific recommendation for booster doses. However, both companies are developing vaccines that could be administered as boosters, and that also have coverage for emerging variants of SARS-CoV-2 less susceptible to vaccine inhibition. (Last reviewed/updated on 24 Feb 2021)”
 

House Cat

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Fully vaccinated people can:

  • Visit with other fully vaccinated people indoors without wearing masks or physical distancing
  • Visit with unvaccinated people from a single household who are at low risk for severe COVID-19 disease indoors without wearing masks or physical distancing
  • Refrain from quarantine and testing following a known exposure if asymptomatic
For now, fully vaccinated people should continue to:

  • Take precautions in public like wearing a well-fitted mask and physical distancing
  • Wear masks, practice physical distancing, and adhere to other prevention measures when visiting with unvaccinated people who are at increased risk for severe COVID-19 disease or who have an unvaccinated household member who is at increased risk for severe COVID-19 disease
  • Wear masks, maintain physical distance, and practice other prevention measures when visiting with unvaccinated people from multiple households
  • Avoid medium- and large-sized in-person gatherings
  • Get tested if experiencing COVID-19 symptoms
  • Follow guidance issued by individual employers
  • Follow CDC and health department travel requirements and recommendations
 

Dancing Fire

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They‘re working on a booster here @MamaBee, talking about giving it in August/September time.
I knew this was gonna happen. It ain't gonna end with just two shots.
 
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