Calling msop04....pharmacy question please...

[Missy]

Hi I have a pharmaceutical question about a medication I am taking and I hope it is OK to ask you offline. I contacted you via loupe troop.

Thanks so much and hope you don't mind me contacting you about this.

If you don't get it (as I know loupe troop can be wonky at times) here is my info:
https://loupetroop.com/listings/other/for-rainwood-and-aztonie


Best,
Missy

 

[msop04]

Oops! Just now seeing this, @missy -- I haven't received anything from LT, so I'll contact you! No problem at all!

 

[AprilBaby]

I have a pharmacy question. As posted in the other thread: why can one person take a drug such as Vicodin and get “high” and I can take 2-3 and get pain relief and a headache? I was under the assumption it had to do with genetics and opiate receptors. I couldn’t get high if I wanted to. ( which I don’t, I don’t like feeling out of control)

 

[Missy]

Oops! Just now seeing this, @missy -- I haven't received anything from LT, so I'll contact you! No problem at all!

Just wanted to thank you again for your kind and thorough reply. Very generous of you and I so appreciate it msop04! Thank you so much!!!!!

 

[msop04]

I have a pharmacy question. As posted in the other thread: why can one person take a drug such as Vicodin and get “high” and I can take 2-3 and get pain relief and a headache? I was under the assumption it had to do with genetics and opiate receptors. I couldn’t get high if I wanted to. ( which I don’t, I don’t like feeling out of control)

Hey, @AprilBaby! There are a lot of things at play when it come to the desired effect of pain medications (and drugs in general). It could very well be that your opiate receptors aren't taking up the medication as much as those who can "get high". It could also be that you metabolize those types of meds a little differently than others... Honestly, it could be a myriad of things keeping you from feeling the high that others do when taking opiates.

However, when you are in pain and taking the meds to help alleviate/stop it, then you're a lot less likely to get the "high feeling" than those who aren't experiencing any pain and just taking them for fun. Some people just don't get high though... that said, if your pain is being controlled when you take your meds, then they're doing what they're supposed to do. (...but it would be nice to be feel high, amirite?! HA)

ETA: just saw that you don't like feeling out of control, so I guess it's a good thing you don't feel those effects! HA!

I know that's really not a great answer to your question, but just know that you're certainly not the only one who doesn't experience opiate highs.

 

[msop04]

Just wanted to thank you again for your kind and thorough reply. Very generous of you and I so appreciate it msop04! Thank you so much!!!!!

You're so welcome @missy!! Glad to help anytime!

 

[lyra]

That's interesting information. I admit I always wondered about opiates too. I've only had them while in the hospital, but they always just made me sick so I'd beg off. It became a matter of what was worse, the pain, or the meds. I can understand though, that people who are not in pain and are taking things for recreational purposes might have another response.

 

[msop04]

That's interesting information. I admit I always wondered about opiates too. I've only had them while in the hospital, but they always just made me sick so I'd beg off. It became a matter of what was worse, the pain, or the meds. I can understand though, that people who are not in pain and are taking things for recreational purposes might have another response.

Yeah... some people just have a really difficult time with pain meds -- the nausea can be excruciating, even after eating.

 

[AprilBaby]

I metabolize a lot of things differently than the average person. I haVe the red hair gene for pain, I don’t numb easily at the dentist. Right now I’m on two 50 tramadol for my ankle surgery pain and I might as well be on M&M’s.

 

[Calliecake]

@April Baby, Is the tramadol not helping at all? Did the doctor give you any idea when your ankle would begin to feel better?

 

[lyra]

I metabolize a lot of things differently than the average person. I haVe the red hair gene for pain, I don’t numb easily at the dentist. Right now I’m on two 50 tramadol for my ankle surgery pain and I might as well be on M&M’s.

I'm sorry you're in so much pain! No one has ever told me why I metabolize meds differently than expected. I can't take any timed release meds because they just seem to dump immediately. My dentist almost always gives up on numbing and makes me just go with it. Not fun. He's tried everything, nothing works. The morphine I've had gives me a stunning headache and sick stomach. I've never ever been prescribed a pain med stronger than a Tylenol 3. If I'm honest, if I'm in real serious pain that I can't live with, I'll put myself to sleep. Partly because I know my pain comes from inflammation (ankylosing spondylitis + rheumatoid + psoriatic arthritis). I am on a biologic (remicade) and methotrexate. These 2 meds seem to react properly for me. No idea why they are different. I had no idea these sorts of reactions are genetic.

 

[AprilBaby]

There is a gene for red hair, if you have it you don’t get numb. We def have it. I have two red heads. The tramadol helps a little but actually the Tylenol is better. Today I’m not taking anything. The infection is gone away and my. Stitches should come out next Monday.